This course will introduce students to key concepts in cell mechanics and mechanobiology. Topics covered include structure of mammalian cells; cell membrane mechanics; mechanics of the cytoskeleton and nucleus; models of cell viscoelasticity; cell adhesion, cell contraction and spreading; active cell migration and phagocytosis, cellular mechanotransduction, and experimental techniques (micropipette aspiration, biointerface probe, atomic force microscopy, tracking force microscopy, magnetic twisting cytometry, optical tweezers, microfluidic deformability cytometry, and flow chambers)